Key differences, features, and comparative analysis of Disorder and Karyotype.
| Disorder | Karyotype | Features |
|---|---|---|
| Down's syndrome | Trisomy 21 (extra 21) | Short stature, small round head, furrowed protruding tongue, partly open mouth, broad palm with a characteristic crease; retarded mental & physical development. (Described by Langdon Down.) |
| Klinefelter's syndrome | 47, XXY (extra X) | Overall masculine but with some feminine development (gynaecomastia = breast development); sterile. |
| Turner's syndrome | 45, X0 (missing X) | Sterile female; rudimentary ovaries; lack of other secondary sexual characters. |
This comparison table is part of the chapter notes for Principles of Inheritance and Variation. Get complete notes, flashcards, active recall sheets, and test prep modes: