3-4 Questions
Avg NEET Questions/Year
12-16 Marks
Weightage Impact
31 MCQs
Question Bank Size
Key Focus Areas: Immunity (Innate vs Acquired), Plasmodium life cycle, Cancer, AIDS, Drugs & Alcohol.
Complete Human Health & Disease Question Bank & Solutions (31 Questions)
Q1 of 31
NEET NCERT Line-by-Line
Typhoid fever is confirmed by:
(A)
Biopsy
(B)
Widal test
(C)
ELISA
(D)
PCR
Show Answer & NCERT Explanation
Correct Answer: (B) Widal test
Typhoid fever (caused by Salmonella typhi) is confirmed by the Widal test, which detects antibodies against S. typhi in patient's serum.
Q2 of 31
NEET NCERT Line-by-Line
Haemozoin is responsible for:
(A)
Anaemia in malaria
(B)
Chill and high fever in malaria
(C)
Rupture of mosquito salivary glands
(D)
Blocking of liver cells
Show Answer & NCERT Explanation
Correct Answer: (B) Chill and high fever in malaria
Haemozoin is a toxic substance released during rupture of RBCs in malaria. It is responsible for the chill and high fever recurring every three to four days.
Q3 of 31
NEET NCERT Line-by-Line
Interferons are produced by:
(A)
Healthy cells to attract antibodies
(B)
Virus-infected cells to protect non-infected cells
(C)
B-lymphocytes
(D)
T-lymphocytes
Show Answer & NCERT Explanation
Correct Answer: (B) Virus-infected cells to protect non-infected cells
Interferons are proteins secreted by virus-infected cells that protect non-infected cells from further viral infection. They form the cytokine barrier in innate immunity.
Q4 of 31
NEET NCERT Line-by-Line
Antibodies produced during an allergic response are of type:
(A)
IgG
(B)
IgM
(C)
IgA
(D)
IgE
Show Answer & NCERT Explanation
Correct Answer: (D) IgE
Allergens stimulate production of IgE antibodies. IgE binds to mast cells causing release of histamine and serotonin — producing allergic symptoms.
Q5 of 31
NEET NCERT Line-by-Line
The thymus is a primary lymphoid organ. Which cells mature here?
(A)
B-lymphocytes
(B)
T-lymphocytes
(C)
NK cells
(D)
Macrophages
Show Answer & NCERT Explanation
Correct Answer: (B) T-lymphocytes
The thymus provides micro-environment for the development and maturation of T-lymphocytes. It is large at birth and reduces greatly by puberty.
Q6 of 31
NEET NCERT Line-by-Line
Which of the following is NOT a property of malignant tumors?
(A)
Rapid cell division
(B)
Metastasis
(C)
Invasion of surrounding tissue
(D)
Confined to original location
Show Answer & NCERT Explanation
Correct Answer: (D) Confined to original location
Being confined to the original location is the property of benign tumors. Malignant tumors are invasive, grow rapidly, and spread to distant sites through blood (metastasis).
Q7 of 31
NEET NCERT Line-by-Line
Heroin is chemically known as:
(A)
Morphine
(B)
Diacetylmorphine
(C)
Cocaine
(D)
Cannabis
Show Answer & NCERT Explanation
Correct Answer: (B) Diacetylmorphine
Heroin (smack) is chemically diacetylmorphine — obtained by acetylation of morphine extracted from latex of poppy plant Papaver somniferum.
Q8 of 31
NEET NCERT Line-by-Line
HIV primarily attacks which cells?
(A)
B-lymphocytes
(B)
Helper T-lymphocytes (TH)
(C)
Macrophages only
(D)
Red blood cells
Show Answer & NCERT Explanation
Correct Answer: (B) Helper T-lymphocytes (TH)
HIV first replicates in macrophages, then attacks helper T-lymphocytes (TH), progressively reducing their count, causing immune deficiency.
Q9 of 31
NEET NCERT Line-by-Line
Filariasis (elephantiasis) is caused by:
(A)
Ascaris
(B)
Entamoeba histolytica
(C)
Wuchereria bancrofti
(D)
Plasmodium vivax
Show Answer & NCERT Explanation
Correct Answer: (C) Wuchereria bancrofti
Filariasis (elephantiasis) is caused by filarial worms Wuchereria bancrofti and W. malayi, transmitted by female mosquito bite, causing chronic inflammation of lymphatic vessels.
Q10 of 31
NEET NCERT Line-by-Line
α-interferon is used in cancer treatment as:
(A)
Chemotherapy drug
(B)
Biological response modifier in immunotherapy
(C)
Radiotherapy agent
(D)
Hormone therapy
Show Answer & NCERT Explanation
Correct Answer: (B) Biological response modifier in immunotherapy
α-interferon is a biological response modifier used in immunotherapy — it activates the patient's immune system to help recognise and destroy tumor cells.
Q11 of 31
NEET NCERT Line-by-Line
Which of the following is NOT a property of malignant tumors?
(A)
Rapid cell division
(B)
Metastasis
(C)
Invasion of surrounding tissue
(D)
Confined to original location
Show Answer & NCERT Explanation
Correct Answer: (D) Confined to original location
Being confined to the original location is the property of benign tumors. Malignant tumors are invasive, grow rapidly, and spread to distant sites through blood (metastasis).
Q12 of 31
NEET NCERT Line-by-Line
Heroin is chemically known as:
(A)
Morphine
(B)
Diacetylmorphine
(C)
Cocaine
(D)
Cannabis
Show Answer & NCERT Explanation
Correct Answer: (B) Diacetylmorphine
Heroin (smack) is chemically diacetylmorphine — obtained by acetylation of morphine extracted from latex of poppy plant Papaver somniferum.
Q13 of 31
NEET NCERT Line-by-Line
HIV primarily attacks which cells?
(A)
B-lymphocytes
(B)
Helper T-lymphocytes (TH)
(C)
Macrophages only
(D)
Red blood cells
Show Answer & NCERT Explanation
Correct Answer: (B) Helper T-lymphocytes (TH)
HIV first replicates in macrophages, then attacks helper T-lymphocytes (TH), progressively reducing their count, causing immune deficiency.
Q14 of 31
NEET NCERT Line-by-Line
Filariasis (elephantiasis) is caused by:
(A)
Ascaris
(B)
Entamoeba histolytica
(C)
Wuchereria bancrofti
(D)
Plasmodium vivax
Show Answer & NCERT Explanation
Correct Answer: (C) Wuchereria bancrofti
Filariasis (elephantiasis) is caused by filarial worms Wuchereria bancrofti and W. malayi, transmitted by female mosquito bite, causing chronic inflammation of lymphatic vessels.
Q15 of 31
NEET NCERT Line-by-Line
α-interferon is used in cancer treatment as:
(A)
Chemotherapy drug
(B)
Biological response modifier in immunotherapy
(C)
Radiotherapy agent
(D)
Hormone therapy
Show Answer & NCERT Explanation
Correct Answer: (B) Biological response modifier in immunotherapy
α-interferon is a biological response modifier used in immunotherapy — it activates the patient's immune system to help recognise and destroy tumor cells.
Q16 of 31
NEET NCERT Line-by-Line
The typhoid test that detects antibodies against Salmonella is:
(A)
ELISA
(B)
Western blot
(C)
Widal test
(D)
PCR
Show Answer & NCERT Explanation
Correct Answer: (C) Widal test
The Widal test is a serological test that detects antibodies (agglutinins) against Salmonella typhi antigens in the patient's serum, confirming typhoid fever.
Q17 of 31
NEET NCERT Line-by-Line
Allergy involves the release of which chemicals from mast cells?
(A)
Insulin and glucagon
(B)
Histamine and serotonin
(C)
Adrenaline and cortisol
(D)
Thyroxine
Show Answer & NCERT Explanation
Correct Answer: (B) Histamine and serotonin
When allergens bind to IgE on mast cells, the mast cells release histamine and serotonin (from stored granules), causing typical allergy symptoms.
Q18 of 31
NEET NCERT Line-by-Line
Which lymphoid organ is site of maturation for T-lymphocytes?
(A)
Bone marrow
(B)
Spleen
(C)
Thymus
(D)
Lymph nodes
Show Answer & NCERT Explanation
Correct Answer: (C) Thymus
The thymus is the primary lymphoid organ where T-lymphocytes (T-cells) develop and mature. It is large at birth and reduces greatly in size by puberty.
Q19 of 31
NEET NCERT Line-by-Line
Passive immunity is provided by:
(A)
Vaccination
(B)
Exposure to antigen
(C)
Ready-made antibodies transferred into the body
(D)
Memory B cells
Show Answer & NCERT Explanation
Correct Answer: (C) Ready-made antibodies transferred into the body
In passive immunity, ready-made antibodies are directly introduced (not made by the individual). Example: IgA from colostrum; antivenom serum against snake bites.
Q20 of 31
NEET NCERT Line-by-Line
Which of the following is a secondary lymphoid organ?
(A)
Bone marrow
(B)
Thymus
(C)
Spleen
(D)
Bursa of Fabricius
Show Answer & NCERT Explanation
Correct Answer: (C) Spleen
The spleen is a secondary lymphoid organ where mature lymphocytes are activated and interact with antigens. Bone marrow and thymus are primary lymphoid organs.
Q21 of 31
NEET NCERT Line-by-Line
The common cold virus infects:
(A)
Lungs and bronchi
(B)
Nose and respiratory passage only
(C)
Entire digestive system
(D)
Blood and liver
Show Answer & NCERT Explanation
Correct Answer: (B) Nose and respiratory passage only
Rhinoviruses causing common cold infect the nose and respiratory passage but do NOT infect the lungs, which is a key distinction from pneumonia.
Q22 of 31
NEET NCERT Line-by-Line
Which Plasmodium species causes the most malignant form of malaria?
(A)
P. vivax
(B)
P. malariae
(C)
P. ovale
(D)
P. falciparum
Show Answer & NCERT Explanation
Correct Answer: (D) P. falciparum
Plasmodium falciparum causes the most severe (malignant tertian) malaria, which can be fatal. P. vivax causes benign tertian malaria.
Q23 of 31
NEET NCERT Line-by-Line
Humoral immunity is mediated by:
(A)
T-lymphocytes
(B)
NK cells
(C)
B-lymphocytes producing antibodies
(D)
Macrophages
Show Answer & NCERT Explanation
Correct Answer: (C) B-lymphocytes producing antibodies
Humoral immunity is B-lymphocyte mediated. B-cells produce antibodies (immunoglobulins) that circulate in the blood and attack antigens. CMI is T-cell mediated.
Q24 of 31
NEET NCERT Line-by-Line
Genes that when mutated lead to cancerous growth are called:
(A)
Tumour suppressor genes
(B)
Proto-oncogenes
(C)
Antigens
(D)
Interferons
Show Answer & NCERT Explanation
Correct Answer: (B) Proto-oncogenes
Proto-oncogenes are normal genes that regulate cell division. When mutated by carcinogens (chemical, physical, or viral), they become oncogenes, which cause uncontrolled cell division (cancer).
Q25 of 31
NEET NCERT Line-by-Line
Ascariasis is caused by:
(A)
Wuchereria bancrofti
(B)
Entamoeba histolytica
(C)
Ascaris lumbricoides
(D)
Plasmodium falciparum
Show Answer & NCERT Explanation
Correct Answer: (C) Ascaris lumbricoides
Ascariasis is caused by Ascaris lumbricoides (roundworm). It is spread through contaminated soil, water, or vegetables, and causes internal bleeding, muscle pain, and intestinal blockage.
Q26 of 31
NEET NCERT Line-by-Line
Which virus causes AIDS?
(A)
Retrovirus — HTLV
(B)
Retrovirus — HIV (Human Immunodeficiency Virus)
(C)
Adenovirus
(D)
Herpesvirus
Show Answer & NCERT Explanation
Correct Answer: (B) Retrovirus — HIV (Human Immunodeficiency Virus)
AIDS (Acquired Immuno Deficiency Syndrome) is caused by HIV, a retrovirus that uses reverse transcriptase to make DNA from its RNA genome.
Q27 of 31
NEET NCERT Line-by-Line
ELISA test is used for diagnosing:
(A)
Typhoid
(B)
AIDS (HIV infection)
(C)
Malaria
(D)
Ringworm
Show Answer & NCERT Explanation
Correct Answer: (B) AIDS (HIV infection)
ELISA (Enzyme Linked Immunosorbent Assay) is used to confirm HIV infection by detecting anti-HIV antibodies in the patient's serum.
Q28 of 31
NEET NCERT Line-by-Line
Opium is derived from which plant?
(A)
Cannabis sativa
(B)
Erythroxylum coca
(C)
Papaver somniferum
(D)
Atropa belladonna
Show Answer & NCERT Explanation
Correct Answer: (C) Papaver somniferum
Opium and its derivative morphine (and heroin) are obtained from the latex of the poppy plant Papaver somniferum.
Q29 of 31
NEET NCERT Line-by-Line
Cannabis sativa is the source of which drug?
(A)
Heroin
(B)
Cocaine
(C)
Cannabinoids (marijuana)
(D)
Morphine
Show Answer & NCERT Explanation
Correct Answer: (C) Cannabinoids (marijuana)
Cannabinoids (hashish, marijuana, ganja, charas) are obtained from Cannabis sativa plant and generally taken by inhalation or oral ingestion.
Q30 of 31
NEET NCERT Line-by-Line
Rheumatoid arthritis is an example of:
(A)
Allergy
(B)
Acquired immunity failure
(C)
Autoimmune disease
(D)
Innate immunity failure
Show Answer & NCERT Explanation
Correct Answer: (C) Autoimmune disease
Rheumatoid arthritis is an autoimmune disease where the immune system attacks the body's own joint tissues (self-attack), causing inflammation and damage.
Q31 of 31
NEET NCERT Line-by-Line
What percentage of all human lymphoid tissue is MALT (Mucosa-Associated Lymphoid Tissue)?
(A)
10%
(B)
25%
(C)
50%
(D)
75%
Show Answer & NCERT Explanation
Correct Answer: (C) 50%
MALT (Mucosa-Associated Lymphoid Tissue) constitutes approximately 50% of the lymphoid tissue in the human body, lining the gut, respiratory, and urogenital tracts.