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NCERT Comparison Sheet

Disease vs Pathogen

Key differences, features, and comparative analysis of Disease and Pathogen.

DiseasePathogenTransmissionKey Symptoms
TyphoidSalmonella typhi (bacterium)Contaminated food/waterSustained high fever 39–40°C, intestinal perforation. Confirmed by Widal test.
PneumoniaStreptococcus pneumoniae, Haemophilus influenzaeInhaling droplets; sharing utensilsFever, chills, cough; alveoli fill with fluid; lips/nails turn gray/bluish.
Common ColdRhino virusesContaminated objects, dropletsNasal congestion, sore throat, cough; lasts 3–7 days. Infects nose/respiratory passage only, NOT lungs.
MalariaPlasmodium spp. (protozoan); P. falciparum = most deadlyFemale Anopheles mosquito (vector)Chill and high fever every 3–4 days due to haemozoin release.
AmoebiasisEntamoeba histolyticaContaminated food/water; houseflies as mechanical carriersConstipation, abdominal pain, stools with mucous and blood.
AscariasisAscaris (roundworm)Contaminated soil/water/plantsInternal bleeding, muscle pain, fever, anaemia, intestinal blockage.
Filariasis (Elephantiasis)Wuchereria bancrofti / W. malayiFemale mosquito biteChronic inflammation of lymphatic vessels of lower limbs; gross deformity.
RingwormFungi: Microsporum, Trichophyton, EpidermophytonSoil; shared towels/combsDry, scaly lesions on skin, nails, scalp; intense itching.

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